Tier A

Astaxanthin (Haematococcus pluvialis natural)

Also known as: 3,3'-Dihydroxy-β,β-carotene-4,4'-dione · Natural astaxanthin

51 PMID anchor · SKIN · VISION · CARDIO · ENDO · MUSCULO · REPRO · IMMUNE · MITO · Last reviewed 2026-05-23

Read full dossier → Deep-dive article → JSON (astaxanthin.json)

Mechanism of action

Singlet oxygen quenching
NF-κB inhibition
NRF2 activation
PPAR-α modulation
Collagen synthesis support

Molecular + tissue targets

Mitochondria
Cell membrane lipid layer
Oxidative stress markers

Dosage range

6-12 mg/day with food (educational reference)

Safety notes

GRAS at ≤12 mg/day · EU EFSA Novel Food market access authorized (Reg 2015/2283 · ≠ Reg 432/2012 authorized health claim · no EFSA-approved health claim for astaxanthin) · theoretical anticoagulant interaction · consult healthcare provider for pregnancy/lactation/ART

Cross-market regulatory status

🇺🇸 FDA

GRAS NDI (Haematococcus pluvialis source)

🇪🇺 EFSA

Novel Food market access authorized (Reg 2015/2283 · Haematococcus pluvialis source · ≤ 8 mg/day food supplement limit per EFSA opinion) · NO authorized health claim under Reg 432/2012 (no EFSA-approved structure/function or health claim for astaxanthin)

🇧🇷 ANVISA

RDC 243/2018 dietary supplement · IN 28/2018 Anexo I authorized constituent (Haematococcus pluvialis source) · Anexo IV upper limit 6 mg/dia · NO Anexo V alegação funcional for astaxantina

Common use cases

skin moisture/elasticity
eye-protection
cardiovascular markers
fatigue/recovery
PCOS reproductive markers

Cross-reference

Health goals: skin beauty eye protection heart health longevity stack reproductive health

Lifestyles: senior 60 plus athletic performance pregnancy

Full dossier: /ingredients/astaxanthin/

Machine-readable JSON: /api/nc/astaxanthin.json