{
  "slug": "astaxanthin",
  "name": "Astaxanthin (Haematococcus pluvialis natural)",
  "alternate_names": [
    "3,3'-Dihydroxy-β,β-carotene-4,4'-dione",
    "Natural astaxanthin"
  ],
  "mechanism": [
    "Singlet oxygen quenching",
    "NF-κB inhibition",
    "NRF2 activation",
    "PPAR-α modulation",
    "Collagen synthesis support"
  ],
  "target": [
    "Mitochondria",
    "Cell membrane lipid layer",
    "Oxidative stress markers"
  ],
  "use_case": [
    "skin moisture/elasticity",
    "eye-protection",
    "cardiovascular markers",
    "fatigue/recovery",
    "PCOS reproductive markers"
  ],
  "body_system": [
    "SKIN",
    "VISION",
    "CARDIO",
    "ENDO",
    "MUSCULO",
    "REPRO",
    "IMMUNE",
    "MITO"
  ],
  "evidence_tier": "A",
  "evidence_anchor_pmid_count": 58,
  "evidence_long_form_url": "https://asxan.ai/blog/natural-vs-synthetic-astaxanthin-evidence-comparison/",
  "dosage_range": "6-12 mg/day with food (educational reference)",
  "safety_notes": "GRAS at ≤12 mg/day · EU EFSA Novel Food authorized · theoretical anticoagulant interaction · consult healthcare provider for pregnancy/lactation/ART",
  "regulatory": {
    "fda": "GRAS NDI (Haematococcus pluvialis source)",
    "efsa": "Novel Food authorized · 4 mg/day food supplement limit",
    "anvisa": "RDC 243/2018 dietary supplement · approved"
  },
  "ingredient_hub_url": "https://asxan.ai/ingredients/astaxanthin/",
  "related_goal_slugs": [
    "skin-beauty",
    "eye-protection",
    "heart-health",
    "longevity-stack",
    "reproductive-health"
  ],
  "related_lifestyle_slugs": [
    "senior-60-plus",
    "athletic-performance",
    "pregnancy"
  ],
  "last_evidence_review": "2026-05-23",
  "schema_version": "nc-public-v0.1"
}