🇺🇸 FDA
GRAS · DSHEA dietary supplement · no specific health claim · qualifies for 21 CFR 101.79 "good source of protein" (≥ 10% DV) when serving size meets the threshold
Plant Protein Blend (Pea + Rice + Hemp + Soy combinations)
Also known as: Vegan protein blend · Plant-based protein · Multi-source plant protein
Mechanism of action
- Combination of plant proteins balances limiting amino acids (legume methionine deficit complemented by cereal lysine deficit)
- Leucine threshold reached at higher absolute doses (~30-40 g) than dairy-based proteins
- mTORC1 activation comparable to milk protein when blended and dose-matched
Molecular + tissue targets
- Skeletal muscle protein synthesis
- Plant-based dietary protein adequacy
- Whole-body amino acid balance for diverse diets
Dosage range
30-40 g per serving (Reid-McCann 2025 PMID 39813010 Nutrition Reviews SR + meta-analysis of 43 RCT · 30 in meta showed animal protein favoured for muscle mass while no significant difference for muscle strength); 1.2-1.6 g/kg/day total when relying on plant blends
Safety notes
Common plant allergens may be present depending on the blend formula (soy / pea / wheat); blends should disclose individual sources for allergen-aware adults; PDCAAS varies by formulation with well-formulated blends approaching 0.9-1.0
Cross-market regulatory status
🇪🇺 EFSA
Authorized protein claims (Reg 432/2012) for muscle mass + bone maintenance available when food source provides ≥ 12% energy from protein
🇧🇷 ANVISA
RDC 243/2018 dietary supplement · IN 28/2018 Anexo V alegação funcional verbatim: "As proteínas auxiliam na formação dos músculos e ossos." (Anexo III ≥ 8,4 g/dia adultos ≥ 19 anos · Anexo VII proteína de referência AAE/g)
Authorized claims · verbatim (4)
Direct quotes from each jurisdiction's framework · never paraphrased · with framework reference and conditions of use.
🇪🇺 EFSA · 3 claims
Reg 432/2012
Protein contributes to a growth in muscle mass.
Conditions: Reg 1924/2006 art 10(2) + Annex: claim may only be used for food which is at least a "source of protein" — ≥ 12% of energy value provided by protein
Authorized 2012
Reg 432/2012
Protein contributes to the maintenance of muscle mass.
Conditions: Reg 1924/2006 art 10(2) + Annex: claim may only be used for food which is at least a "source of protein" — ≥ 12% of energy value provided by protein
Authorized 2012
Reg 432/2012
Protein contributes to the maintenance of normal bones.
Conditions: Reg 1924/2006 art 10(2) + Annex: claim may only be used for food which is at least a "source of protein" — ≥ 12% of energy value provided by protein
Authorized 2012
🇧🇷 ANVISA · 1 claim
IN 28/2018 Anexo V alegação funcional
As proteínas auxiliam na formação dos músculos e ossos.
Conditions: IN 28/2018 Anexo V: alegação restrita aos suplementos cuja quantidade de proteína e perfil de aminoácidos essenciais atendam os Anexos III + VII
Authorized 2018
Common use cases
- plant-based diet protein adequacy
- dairy / animal allergen avoidance
- sustainable dietary pattern support
- sarcopenia prevention
Cross-reference
Health goals: athletic performance weight management longevity stack menopause support
Lifestyles: plant based athletic performance senior 60 plus
Full dossier: /ingredients/plant-protein/
Machine-readable JSON: /api/nc/plant-protein.json