🇺🇸 FDA
GRAS · DSHEA dietary supplement; structure/function claims permitted
CoQ10 (Ubiquinone / Ubiquinol)
Also known as: Coenzyme Q10 · Ubiquinone-10 · Ubidecarenone · Ubiquinol (reduced form)
Mechanism of action
- Mitochondrial electron transport chain (Complex I-III shuttle)
- Lipid-phase antioxidant
- ATP biosynthesis cofactor
- Statin-induced CoQ10 depletion rescue
Molecular + tissue targets
- Mitochondrial bioenergetics
- Cardiac myocyte ATP
- Endothelial function
Dosage range
100-300 mg/day ubiquinone; 100-200 mg/day ubiquinol (better absorbed >50yo); Q-SYMBIO HF 100 mg t.i.d.
Safety notes
Generally well tolerated; theoretical warfarin interaction (vitamin K-like quinone structure); take with fat for absorption
Cross-market regulatory status
🇪🇺 EFSA
No authorized health claim (claims rejected 2010); permitted as food supplement
🇧🇷 ANVISA
RDC 243/2018 dietary supplement · IN 28/2018 alegação funcional not authorized
Common use cases
- statin-associated muscle symptoms (research context)
- heart failure adjunct (Q-SYMBIO 2014)
- mitochondrial support
- fertility (research context)
Cross-reference
Health goals: heart health longevity stack athletic performance reproductive health
Lifestyles: senior 60 plus senior 60 plus high stress
Full dossier: /ingredients/coq10/
Machine-readable JSON: /api/nc/coq10.json