🇺🇸 FDA
GRAS notification GRN 765 (hemp seed and hemp seed-derived ingredients) · DSHEA dietary supplement · no specific health claim
Hemp Protein (Cannabis sativa Seed Protein)
Also known as: Hemp seed protein · Hemp seed meal · Cannabis sativa L. seed protein
Mechanism of action
- Plant protein delivered with native fibre and omega-3 ALA content from the seed matrix
- mTORC1 activation theoretically possible but no human dose-response RCT in muscle protein synthesis context
Molecular + tissue targets
- Plant-based dietary protein contribution
- Dietary fibre / ALA intake when consumed as whole-seed meal
Dosage range
No published human RCT establishes a specific muscle-protein dose. Per-serving 20-30 g typical in commercial products. House 2010 PMID 20977230 J Agric Food Chem rat bioassay reported PDCAAS 0.49-0.66 across whole / meal / dehulled hemp seed, with dehulled hemp showing the best digestibility-corrected score
Safety notes
Tetrahydrocannabinol residues should be at or below jurisdictional thresholds — choose products with COA disclosure for THC; relatively low PDCAAS makes blending with complementary plant proteins advisable for those relying on hemp as the primary protein source
Cross-market regulatory status
🇪🇺 EFSA
Authorized protein claims (Reg 432/2012) for muscle mass + bone maintenance available when food source provides ≥ 12% energy from protein
🇧🇷 ANVISA
RDC 243/2018 dietary supplement · IN 28/2018 Anexo V alegação funcional verbatim: "As proteínas auxiliam na formação dos músculos e ossos." (Anexo III ≥ 8,4 g/dia adultos ≥ 19 anos · Anexo VII proteína de referência AAE/g)
Authorized claims · verbatim (4)
Direct quotes from each jurisdiction's framework · never paraphrased · with framework reference and conditions of use.
🇪🇺 EFSA · 3 claims
Reg 432/2012
Protein contributes to a growth in muscle mass.
Conditions: Reg 1924/2006 art 10(2) + Annex: claim may only be used for food which is at least a "source of protein" — ≥ 12% of energy value provided by protein
Authorized 2012
Reg 432/2012
Protein contributes to the maintenance of muscle mass.
Conditions: Reg 1924/2006 art 10(2) + Annex: claim may only be used for food which is at least a "source of protein" — ≥ 12% of energy value provided by protein
Authorized 2012
Reg 432/2012
Protein contributes to the maintenance of normal bones.
Conditions: Reg 1924/2006 art 10(2) + Annex: claim may only be used for food which is at least a "source of protein" — ≥ 12% of energy value provided by protein
Authorized 2012
🇧🇷 ANVISA · 1 claim
IN 28/2018 Anexo V alegação funcional
As proteínas auxiliam na formação dos músculos e ossos.
Conditions: IN 28/2018 Anexo V: alegação restrita aos suplementos cuja quantidade de proteína e perfil de aminoácidos essenciais atendam os Anexos III + VII
Authorized 2018
Common use cases
- plant-based diet protein contribution
- fibre + omega-3 ALA addition (whole-seed meal context)
- blended formulations with pea / rice for completeness
Cross-reference
Health goals: athletic performance weight management
Lifestyles: plant based
Full dossier: /ingredients/hemp-protein/
Machine-readable JSON: /api/nc/hemp-protein.json