{
  "authorized_claims": [
    {
      "market": "EFSA",
      "framework_reference": "Reg 432/2012",
      "claim_verbatim": "Protein contributes to a growth in muscle mass.",
      "authorization_date": "2012"
    },
    {
      "market": "EFSA",
      "framework_reference": "Reg 432/2012",
      "claim_verbatim": "Protein contributes to the maintenance of muscle mass.",
      "authorization_date": "2012"
    },
    {
      "market": "EFSA",
      "framework_reference": "Reg 432/2012",
      "claim_verbatim": "Protein contributes to the maintenance of normal bones.",
      "authorization_date": "2012"
    },
    {
      "market": "ANVISA",
      "framework_reference": "IN 28/2018 alegação funcional",
      "claim_verbatim": "As proteínas auxiliam na formação dos músculos e ossos. Seu consumo deve estar associado a uma alimentação equilibrada e hábitos de vida saudáveis.",
      "authorization_date": "2018"
    }
  ],
  "slug": "whey-protein",
  "name": "Whey Protein (WPC · WPI · WPH · Native)",
  "alternate_names": [
    "Whey protein concentrate",
    "Whey protein isolate",
    "Whey protein hydrolysate"
  ],
  "mechanism": [
    "mTORC1 activation",
    "Leucine triggering of MPS",
    "GLP-1/GIP incretin response",
    "Rapid amino acid delivery"
  ],
  "target": [
    "Skeletal muscle protein synthesis",
    "Incretin axis",
    "Glycemic regulation"
  ],
  "use_case": [
    "muscle protein synthesis",
    "sarcopenia prevention",
    "GLP-1 companion adequacy",
    "recovery"
  ],
  "body_system": [
    "MUSCULO",
    "METABOLISM",
    "ENDO"
  ],
  "evidence_tier": "A",
  "evidence_anchor_pmid_count": 39,
  "evidence_long_form_url": "https://asxan.ai/blog/protein-source-decision-tree-whey-vs-yeast-focus/",
  "dosage_range": "20-40 g/serving (Macnaughton 2016 RCT 40 g optimal whole-body MPS); daily protein target 1.2-1.6 g/kg/day (Morton 2018 meta)",
  "safety_notes": "Lactose intolerance in WPC · acid-ash dietary debunked (Fenton 2009) · healthy-kidney rebuttal (Devries 2018 meta)",
  "regulatory": {
    "fda": "GRAS · food ingredient · DSHEA dietary supplement",
    "efsa": "Authorized claim for protein contribution to muscle mass + bone health",
    "anvisa": "RDC 243/2018 dietary supplement · IN 28/2018 authorized claim"
  },
  "ingredient_hub_url": "https://asxan.ai/ingredients/whey-protein/",
  "related_goal_slugs": [
    "athletic-performance",
    "glp-1-companion",
    "healthy-aging",
    "weight-management"
  ],
  "related_lifestyle_slugs": [
    "athletic-performance",
    "senior-60-plus",
    "glp-1-companion"
  ],
  "last_evidence_review": "2026-05-24",
  "schema_version": "nc-public-v0.1"
}