{
  "slug": "nervonic-acid",
  "name": "Nervonic Acid",
  "alternate_names": [
    "C24:1n-9",
    "cis-15-tetracosenoic acid",
    "Selacholeic acid",
    "Acer truncatum seed oil (carrier)",
    "Malania oleifera oil (carrier)"
  ],
  "mechanism": [
    "Ultra-long-chain MUFA structural component of myelin sphingolipids (sphingomyelin/cerebrosides)",
    "Proposed support of myelin sheath integrity and remyelination (preclinical/observational)",
    "Neuronal membrane and white-matter fatty-acid composition modulation (research-context)"
  ],
  "target": [
    "Myelin sphingolipid pool / white-matter integrity",
    "Brain ultra-long-chain fatty-acid composition",
    "Neural signal-conduction substrate (preclinical)"
  ],
  "use_case": [
    "myelin / white-matter support (preclinical & observational research-context)",
    "cognitive / brain-aging association (observational research-context)",
    "neurodevelopment fatty-acid supply (research-context)"
  ],
  "body_system": [
    "BRAIN",
    "NERVOUS"
  ],
  "evidence_tier": "C",
  "evidence_anchor_pmid_count": 0,
  "dosage_range": "No established human supplemental dose. Acer truncatum seed oil products typically standardized to ~5-6% nervonic acid; studied human evidence is preliminary/observational. Educational reference only, not a dosing recommendation.",
  "safety_notes": "Consumed as a minor constituent of edible carrier oils (Acer truncatum seed oil approved as a Novel Food in China) with limited isolated-compound safety data. Human RCT evidence is lacking; mechanistic and observational data only. Not characterized for pregnancy/lactation. Educational information, not medical advice; not intended to diagnose, treat, cure, or prevent disease.",
  "regulatory": {
    "fda": "No FDA GRAS determination for isolated nervonic acid; some Acer truncatum (yuanbaofeng) seed oil products marketed as DSHEA dietary supplements with structure/function claims only; no FDA-authorized health claim.",
    "efsa": "No EFSA-authorized health claim; Acer truncatum / Malania seed oil as a source may fall under EU Novel Food regulation requiring EFSA assessment, not currently authorized.",
    "anvisa": "No specific ANVISA registration or authorized functional claim identified for nervonic acid or Acer truncatum seed oil in Brazil.",
    "cn": "Carrier oil Acer truncatum (yuanbaofeng) seed oil approved as Novel Food ingredient in China (2011 announcement); nervonic acid is its signature functional constituent."
  },
  "regulatory_markets": [
    {
      "market": "CN",
      "status": "Novel Food",
      "tier": "permitted"
    }
  ],
  "authorized_claims": [],
  "ingredient_hub_url": "https://asxan.ai/ingredients/nervonic-acid/",
  "related_goal_slugs": [
    "cognitive-support"
  ],
  "related_lifestyle_slugs": [
    "senior-60-plus"
  ],
  "last_evidence_review": "2026-06-21",
  "schema_version": "nc-public-v0.2",
  "api_version": "nc-public-v0.3",
  "_meta": {
    "last_evidence_review": "2026-06-21",
    "ip_axes_disclosed": {
      "public_axes": [
        "mechanism",
        "target",
        "use_case",
        "body_system",
        "evidence_tier",
        "dosage_range",
        "safety_notes",
        "regulatory",
        "authorized_claims"
      ],
      "ip_axes_not_exposed": [
        "proprietary_formula_ratios",
        "clinical_protocol_internals",
        "proprietary_research_compounds",
        "supplier_specific_grade_specifications",
        "unpublished_endpoint_data"
      ],
      "rationale": "asxan.ai surfaces the educational, evidence-tier-disclosed slice. Formula composition and clinical-protocol internals are intentionally outside this public surface."
    }
  }
}