{
  "slug": "collagen-peptides",
  "name": "Collagen Peptides (Hydrolyzed Type I/II/III)",
  "alternate_names": [
    "Hydrolyzed collagen",
    "Collagen hydrolysate",
    "Bioactive collagen peptides (BCP)"
  ],
  "mechanism": [
    "Bioactive dipeptide/tripeptide absorption (Pro-Hyp · Hyp-Gly)",
    "Dermal fibroblast collagen synthesis stimulation",
    "Chondrocyte matrix turnover signaling",
    "Glycine + proline + hydroxyproline amino acid supply"
  ],
  "target": [
    "Dermal extracellular matrix",
    "Articular cartilage",
    "Connective tissue"
  ],
  "use_case": [
    "skin elasticity/hydration",
    "joint comfort (research context)",
    "connective tissue support"
  ],
  "body_system": [
    "SKIN",
    "MUSCULO",
    "CONNECTIVE"
  ],
  "evidence_tier": "B",
  "evidence_anchor_pmid_count": 28,
  "dosage_range": "2.5-10 g/day hydrolyzed collagen peptides; 40 mg/day UC-II undenatured Type II for joint comfort RCTs",
  "safety_notes": "Generally well tolerated; bovine/marine/porcine source allergens possible; vegan-incompatible (animal-derived)",
  "regulatory": {
    "fda": "GRAS · DSHEA dietary supplement; structure/function claims permitted",
    "efsa": "No authorized health claim (collagen-specific claims rejected 2011)",
    "anvisa": "RDC 243/2018 dietary supplement · IN 28/2018 alegação funcional not authorized for collagen"
  },
  "ingredient_hub_url": "https://asxan.ai/ingredients/collagen-peptides/",
  "related_goal_slugs": [
    "skin-beauty",
    "joint-bone",
    "athletic-performance"
  ],
  "related_lifestyle_slugs": [
    "senior-60-plus",
    "menopause",
    "athletic-performance"
  ],
  "last_evidence_review": "2026-05-29",
  "schema_version": "nc-public-v0.1",
  "api_version": "nc-public-v0.3",
  "_meta": {
    "last_evidence_review": "2026-05-29",
    "ip_axes_disclosed": {
      "public_axes": [
        "mechanism",
        "target",
        "use_case",
        "body_system",
        "evidence_tier",
        "dosage_range",
        "safety_notes",
        "regulatory",
        "authorized_claims"
      ],
      "ip_axes_not_exposed": [
        "proprietary_formula_ratios",
        "clinical_protocol_internals",
        "rnd_pipeline_compounds",
        "supplier_specific_grade_specifications",
        "unpublished_endpoint_data"
      ],
      "rationale": "asxan.ai surfaces the educational, evidence-tier-disclosed slice. Formula composition, clinical-protocol internals, and RnD pipeline data are intentionally outside this public surface."
    }
  }
}